Next-Generation Sequencing (NGS)

Treatment up to Age 56 years old100% Anonymous Donor OptionsEU Standard Care (ISO Certified)Immediate Start (No Waiting Lists)Save ~60% vs. UK/EU Prices

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What is Next-Generation Sequencing (NGS)?

The most recent technology, NGS, allows for 99.99% accuracy in examining all 23 pairs of chromosomes, including sex chromosomes. It is the most sophisticated, enlightening, and trustworthy approach out there.

NGS, which is based on figuring out the DNA sequence, is essentially different from previous PGD techniques in that it offers a more thorough analysis of the genetic composition of the embryos. It enables experts to identify diversity in embryos, for example. Partial anomalies in the embryo’s genetic makeup are known as mosaicism, and they may result in miscarriage or the birth of a child with serious illnesses.

The Benefits of NGS in IVF

1. Increases the chances of embryo implantation and, consequently, positive outcomes
2. Reduces the risk of miscarriage
3. Decreases the likelihood of failed IVF attempts
4. Lowers the risk of children being born with chromosomal abnormalities
5. Eliminates the need for screening and diagnostic tests during pregnancy, thereby reducing the cost of pregnancy follow-up

Types of NGS Tests in IVF

Preimplantation Genetic Testing for Aneuploidy (PGT-A)

A next-generation sequencing (NGS) test called PGT-A examines embryos to check for aneuploidy, which is caused by improperly duplicated, hybridized, or twisted chromosomes. Reproductive endocrinologists can select the highest-quality embryos to transfer and increase the chances of a healthy pregnancy by identifying embryos with the appropriate number of chromosomes.

Preimplantation Genetic Testing for Monogenic Disorders (PGT-M)

A specific NGS test called PGT-M can identify single-gene diseases including sickle cell disease and cystic fibrosis. The fertility specialist can utilize this information to find, pick, and select genetically normal embryos, giving the families a chance to have a healthy child.

Preimplantation Genetic Testing for Structural Rearrangements (PGT-SR)

A type of NGS test called PGT-SR is used to find balanced chromosomal rearrangements that may impact fertility, cause miscarriages, or result in the birth of a child with a genetic defect. Fertility professionals can take part in the well-informed decision-making process on which embryos to transfer when certain structural chromosomal abnormalities are identified.

In Summary

The IVF environment has been completely changed by next-generation sequencing, which also gives fertility specialists a previously unheard-of grasp of the genetic composition of embryos, enabling them to create more individualized, effective, and successful treatment plans. Our clinic is committed to helping couples and families who want to build a family while protecting the health and safety of both parents and children by utilizing this cutting-edge technology.

If you would like to learn more about how Next-Generation Sequencing can improve your fertility journey, we invite you to schedule a Free consultation with our team of experienced fertility specialists and genetic counselors.

Treatment Process

Sample Collection

The NGS process begins with the recovery of a small number of cells, such as those from an embryo biopsy. In order to minimize any disturbance to the embryo’s growth, this biopsy is carried out during the IVF procedure.

DNA Extraction and Library Preparation

Following the recovery of the biopsy sample, the DNA is extracted and ready for sequencing. To extract the genetic material and create a library of interrogable DNA sequences, several laboratory techniques are needed.

Sequencing

High-throughput sequencing, which uses the newest technologies to swiftly and accurately identify the genetic information present in the sample, is the next step in processing the hybridized DNA library.

Data Analysis and Interpretation

Bioinformatic experts then thoroughly review all of the data gathered from the sequencing process, using specialized software and algorithms to find any genetic variations or anomalies on the embryo’s DNA.

Testimonials

Against all odds at age 50

“A professional and very nice experience with the staff. It is like a fairytale—we got help to bring our twins into the world. The second try worked, even against all odds when we were at the age of 50. Now they are 7 months old and we are so happy for all the help.”

Frequently Asked questions

How do you get to our clinic?

Our clinic's location in the Famagusta (Gazimağusa), Glapsides region of Northern Cyprus puts you within easy reach of the area's best swimming beaches, restaurants, and resorts, allowing you to relax and unwind during your stay.

Most of our international patients fly into one of two airports

Ercan Airport (ECN)

Located in Northern Cyprus, this is the most convenient option and is only a 40-minute drive from our clinic.

Larnaca Airport (LCA)

Located in the South of Cyprus, this is another popular option depending on your passport and flight availability.

A Seamless Journey, Arranged For You

To ensure your experience is completely stress-free from the moment you book your flights, your dedicated Patient Coordinator will manage all of your logistical arrangements. We handle every detail so you can focus on your treatment.

Our comprehensive service includes

Private Airport Transfers

We will arrange for a driver to meet you upon arrival and transport you directly to your accommodation and appointments.

Accommodation

We can recommend and assist with booking your stay from a wide range of high-quality hotels, apartments, and boutique options that meet our standards for comfort and convenience.

All Local Arrangements

From your arrival until your departure, we ensure every detail of your visit is thoughtfully managed.

Simply share your travel plans with your coordinator, and we will handle the rest.

What is the process for using a donor and what information is provided?

For patients requiring an egg or sperm donor, we have a comprehensive and carefully managed donor programme. The process is governed by strict local regulations that ensure complete donor anonymity.

Our donors undergo rigorous screening, including extensive medical, genetic, and psychological evaluations, to ensure the highest standards of quality and safety. While the donor's identity remains anonymous, you will be provided with a detailed, non-identifying profile which typically includes:

Age and physical characteristics (hair/eye colour, height, build)
Blood type
Nationality and educational background
Profession and personal interests/hobbies

This allows you to choose a donor with characteristics that are important to you while respecting the legal framework of anonymity.

How do you manage treatment for international patients travelling to North Cyprus?

We specialize in making the process seamless for our international patients. Your journey is managed by a dedicated International Patient Coordinator who will be your single point of contact.

After your initial consultation, we will create your bespoke treatment plan.

We offer two flexible pathways for our patients travelling from abroad.

1. The Coordinated Pathway (1-Week Stay in Cyprus)

For your convenience, you can begin the initial stages of your treatment at home. We will coordinate with a clinic in your home country for your preliminary scans and tests. You then travel to Cyprus to complete the final stages, requiring a stay of as little as one week for your key procedures. This option is popular as it minimizes your time away from home.

2. The Immersive Pathway (3-Week Stay in Cyprus)

Alternatively, you can choose to undertake your entire treatment cycle with us in Cyprus. This allows you to step away from daily routines and relax in our calm, supportive environment. This all-inclusive pathway typically requires a stay of approximately three weeks.

Whichever pathway you choose, your coordinator will assist with planning your trip, providing recommendations for premium accommodation and organizing private airport transfers. Our goal is to manage all the logistics, allowing you to focus completely on your treatment in a calm, stress-free environment.

What are your success rates and how can we trust them?

This is often the first and most important question we receive. While we are proud of our excellent success rates, which are in line with top European clinics, we believe in providing you with a transparent and realistic perspective. Rather than focusing on a single, generic statistic, we provide a personalized success projection during your initial consultation. This is based on your specific age, medical history, and diagnosis.

Our success is built upon the expertise of our world-class clinicians and embryologists, who utilize state-of-the-art laboratory technology. We are committed to ethical and transparent reporting, ensuring you have the confidence and clarity you need to make an informed decision.

Tests & Treatments

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